A 22-year-old female was taken to the emergency room in coma. Her parents noticed that she had for the past 1 month polydipsia, polyuria, and rapid weight loss. These symptoms had worsened in the last week. She had not been taking any medications and the clinical history was otherwise unremarkable. On examination, breathing was deep and rapid (Kussmaul respiration), pulse rate was 104 beats per minute, and blood pressure 110/70 mmHg; she also revealed a mildly dehydrated patient. She was drowsy and confused. Rapid hematology and biochemical tests showed
Hematocrit 46%
Hemoglobin 13 g/dl (140 g/L)
White blood cell count 11,000/ μl
Glucose 520 mg/dl (28.9 mmol/L)
Urea 50 mg/dl (8.5 mmol/L)
Creatinine 0.8 mg/dl (70.7 μmol/L)
Na+ 148 mEq/L
K+ 4.6 mEq/L
PO4 3-2.0 mEq/L (0.64 mmol/L)
Cl− 112 mmol/L
Arterial pH was 7.0
PO 2 98 mmHg
PCO 2 25 mmHg
HCO 3−12 mEq/L
O 2 sat 98%.
What’s the diagnosis?
A. Cerebral edema
B. Rhabdomyolysis
C. Acute pancreatitis
D. Sepsis
E. Acute abdomen
F. Diabetic Ketoacidosis
G. Alcoholic ketoacidosis